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Rituximab

PGxPredict™:RITUXIMAB Test - Opening the door to new information for patients and physicians in the treatment of non-Hodgkin’s lymphoma.

Rituximab is an immunotherapeutic agent indicated for the treatment of follicular, CD20-positive B-cell non-Hodgkin’s lymphoma. Rituximab monotherapy has been shown to be effective only in up to 57% of cases,1and can cause serious side effects, some of which could be life-threatening.2 Side effects and the drug's cost may make rituximab a difficult choice for many practitioners and patients.

The PGxPredict:RITUXIMAB test is changing the rules, making it possible to provide patients and physicians with specific information about the likelihood of response to rituximab monotherapy.


References

1 Overall response rate with weekly dosing, measured at week 8 in relapsed or refractory, low grade or follicular, CD20-positive B-cell NHL. (See Rituxan® product insert)

2 In patients treated with single agent rituximab for relapsed or refractory, low-grade of follicular, CD20-positive, B-cell NHL, Grade 3 and 4 adverse events overall were reported in 57% of patients with weekly administration for 4 doses, and in 70% of patients with weekly administration for 8 doses. (See Rituxan® product insert)

Rituximab is sold as Rituxan® in the United States. All trademarks are the property of their respective owners.

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