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About PGxPredict™:WARFARIN

Despite warfarin’s well-established efficacy, determining the correct dose can be a challenge. The correct dose varies widely from patient to patient, and may change with variations in diet and other medications. An incorrect dose can lead to serious side effects, including life-threatening bleeding, or to recurrent clotting and disease.

The optimal maintenance dose of warfarin for each patient is difficult to establish; it can take a month or more of frequent monitoring of the prothrombin time (PT, a test for blood coagulability) before a stable maintenance dose of warfarin is identified. The PGxPredict:WARFARIN test may assist your physician in establishing a safe and effective dose for you.

PGxPredict:WARFARIN test is changing this situation by helping to determine in advance how individual patients are likely to respond to warfarin. This test will help reduce uncertainty and may enable clinicians to provide safer and more effective treatment for their patients. It’s a simple test that may lead to safer treatment and faster recovery.

Patients and Family Members: Frequently asked questions, resources, and more.

Physicians and Healthcare Providers: Instructions for ordering and administering tests, technical specifications, and other resources for healthcare providers.

The US Food and Drug Administration (FDA) has approved updated prescribing information for warfarin to include information on the use of genetic testing (CYP2C9 and VKORC1) to optimize dosing for the management of blood clots and bleeding. Click here for the FDA press release and new label.

 

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